Respiratory Syncytial Virus Activates Rab5a To Suppress IRF1-Dependent Lambda Interferon Production, Subverting the Antiviral Defense of Airway Epithelial Cells

Mo, S; Tang, W; Xie, J; Chen, SS; Ren, L; Zang, N; Xie, XH; Deng, Y; Gao, LQ; Liu, EM

Gao, LQ; Liu, EM (corresponding author), Chongqing Med Univ, Dept Resp Med, Childrens Hosp, Chongqing, Peoples R China.; Gao, LQ; Liu, EM (corresponding author), Natl Clin Res Ctr Child Hlth & Disorders, Chongqing, Peoples R China.; Gao, LQ; Liu, EM (corresponding author), Minist Educ, Key Lab Child Dev & Disorders, Chongqing, Peoples R China.; Gao, LQ; Liu, EM (corresponding author), Chongqing Key Lab Child Infect & Immun, Chongqing, Peoples R China.

JOURNAL OF VIROLOGY, 2021; 95 (8):

Abstract

The limited antiviral options and lack of an effective vaccine against human respiratory syncytial virus (RSV) highlight the need for a novel antivira......

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