Molecular modeling on HIF-2 alpha-ARNT dimer destabilization caused by R171A and/or V192D mutations in HIF-2 alpha

Chen, YJ; Huang, BY; Yang, CN

Yang, CN (reprint author), 700 Kaohsiung Univ Rd, Kaohsiung 811, Taiwan.

JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2018; 79 (): 35

Abstract

Oxygen homeostasis in normal and tumor cells is mediated by hypoxia-inducible factors (HIFs), which are active as heterodimer complexes, such as HIF-2......

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