History and Function of the Lactate Receptor GPR81/HCAR1 in the Brain: A Putative Therapeutic Target for the Treatment of Cerebral Ischemia

Colucci, ACM; Tassinari, ID; Loss, ED; de Fraga, LS

de Fraga, LS (通讯作者),Univ Fed Rio Grande do Sul, Dept Physiol, Rua Ramiro Barcelos 2600,Bldg 21116,Lab 660, BR-90035003 Porto Alegre, Brazil.

NEUROSCIENCE, 2023; 526 (): 144

Abstract

GPR81 isa G-protein coupled receptor (GPCR) discovered in 2001, but deorphanized only 7 years later, when its affinity for lactate as an endogenous li......

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