Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss

Liu, HY; Golji, J; Brodeur, LK; Chung, FS; Chen, JT; deBeaumont, RS; Bullock, CP; Jones, MD; Kerr, G; Li, L; Rakiec, DP; Schlabach, MR; Sovath, S; Growney, JD; Pagliarini, RA; Ruddy, DA; MacIsaac, KD; Korn, JM; McDonald, ER

McDonald, ER (reprint author), Novartis Inst Biomed Res, Oncol Dis Area, Cambridge, MA 02139 USA.

NATURE MEDICINE, 2019; 25 (1): 95

Abstract

Interferons (IFNs) are cytokines that play a critical role in limiting infectious and malignant diseases(1-4). Emerging data suggest that the strength......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索