Carcinoembryonic Antigen (CEA)-Specific 4-1BB-Costimulation Induced by CEA-Targeted 4-1BB-Agonistic Trimerbodies

Mikkelsen, K; Harwood, SL; Compte, M; Merino, N; Molgaard, K; Lykkemark, S; Alvarez-Mendez, A; Blanco, FJ; Alvarez-Vallina, L

Alvarez-Vallina, L (reprint author), Aarhus Univ, Dept Engn, Immunotherapy & Cell Engn Lab, Aarhus, Denmark.; Alvarez-Vallina, L (reprint author), Hosp Univ 12 Octubre, Dept Immunol, Canc Immunotherapy Unit UNICA, Madrid, Spain.; Alvarez-Vallina, L (repri

FRONTIERS IN IMMUNOLOGY, 2019; 10 ():

Abstract

4-1BB (CD137) is an inducible costimulatory receptor that promotes expansion and survival of activated T cells; and IgG-based 4-1BB-agonistic monoclon......

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