CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression

Zaghloul, EM; Gissberg, O; Moreno, PMD; Siggens, L; Hallbrink, M; Jorgensen, AS; Ekwall, K; Zain, R; Wengel, J; Lundin, KE; Smith, CIE

Zaghloul, EM; Smith, CIE (reprint author), Karolinska Inst, Clin Res Ctr, Dept Lab Med, SE-14186 Stockholm, Sweden.; Zaghloul, EM (reprint author), Alexandria Univ, Fac Pharm, Dept Pharmaceut, El Khartoum Sq, Alexandria 21521, Egypt.

NUCLEIC ACIDS RESEARCH, 2017; 45 (9): 5153

Abstract

Huntington's disease (HD) is a fatal, neurodegenerative disorder in which patients suffer from mobility, psychological and cognitive impairments. Exis......

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