Activity of a first-in-class oral HIF2-alpha inhibitor, PT2385, in patients with first recurrence of glioblastoma

Strowd, R; Ellingson, B; Raymond, C; Yao, JW; Wen, PY; Ahluwalia, M; Piotrowski, A; Desai, A; Clarke, JL; Lieberman, FS; Desideri, S; Nabors, LB; Ye, XB; Grossman, S

Strowd, R (通讯作者)，Wake Forest Univ, Sch Med, 1 Med Ctr Blvd, Winston Salem, NC 27157 USA.

JOURNAL OF NEURO-ONCOLOGY, 2023; 165 (1): 101

Abstract

IntroductionHypoxia inducible factor 2-alpha (HIF2 alpha) mediates cellular responses to hypoxia and is over-expressed in glioblastoma (GBM). PT2385 i......

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