Genotoxic stress-activated DNA-PK-p53 cascade and autophagy cooperatively induce ciliogenesis to maintain the DNA damage response

Chen, TY; Huang, BM; Tang, TK; Chao, YY; Xiao, XY; Lee, PR; Yang, LY; Wang, CY

Wang, CY (corresponding author), Natl Cheng Kung Univ, Coll Med, Dept Cell Biol & Anat, Tainan, Taiwan.; Wang, CY (corresponding author), Natl Cheng Kung Univ, Coll Med, Inst Basic Med Sci, Tainan, Taiwan.

CELL DEATH AND DIFFERENTIATION, ; ():

Abstract

The DNA-PK maintains cell survival when DNA damage occurs. In addition, aberrant activation of the DNA-PK induces centrosome amplification, suggesting......

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