Clinical activity of 9-ING-41, a small molecule selective glycogen synthase kinase-3 beta (GSK-3 beta) inhibitor, in refractory adult T-Cell leukemia/lymphoma

Hsu, A; Huntington, KE; De Souza, A; Zhou, LL; Olszewski, AJ; Makwana, NP; Treaba, DO; Cavalcante, L; Giles, FJ; Safran, H; El-Deiry, WS; Carneiro, BA

Carneiro, BA (通讯作者)，Brown Univ, Legorreta Canc Ctr, Lifespan Canc Inst, Div Hematol Oncol, 593 Eddy St,George Bld 302, Providence, RI 02903 USA.

CANCER BIOLOGY & THERAPY, 2022; 23 (1): 417

Abstract

GSK-3 beta is a serine/threonine kinase implicated in tumorigenesis and chemotherapy resistance. GSK-3 beta blockade downregulates the NF-kappa B path......

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