27-Hydroxycholesterol is a specific factor in the neoplastic microenvironment of HCC that causes MDR via GRP75 regulation of the redox balance and metabolic reprogramming

Jin, M; Yang, Y; Dai, Y; Cai, R; Wu, LN; Jiao, YW; Zhang, Z; Yang, HJ; Zhou, Y; Tang, LM; Li, L; Li, Y

Li, Y (通讯作者)，Nanjing Med Univ, Sch Publ Hlth, Collaborat Innovat Ctr Canc Personalized Med, Nanjing 211166, Peoples R China.;Tang, LM (通讯作者)，Nanjing Med Univ, Affiliated Changzhou 2 Hosp, Dept Gen Surg, Changzhou 213003, Jiangsu, Peoples R China.;Li, L (通讯作者)，Nanjing Med Univ, Sch Publ Hlth, Ctr Global Hlth, Nanjing 211166, Peoples R China.

CELL BIOLOGY AND TOXICOLOGY, 2022; 38 (2): 311

Abstract

Objective Due to the tissue specificity of the liver, long-term exposure to a high concentration of 27-hydroxycholesterol (27HC) is a special characte......

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