MYC overexpression leads to increased chromatin interactions at super-enhancers and MYC binding sites

See, YX; Chen, KJ; Fullwood, MJ

Fullwood, MJ (通讯作者)，Nanyang Technol Univ, Sch Biol Sci, Singapore 637551, Singapore.;Fullwood, MJ (通讯作者)，Natl Univ Singapore, Canc Sci Inst Singapore, Singapore 117599, Singapore.;Fullwood, MJ (通讯作者)，Natl Univ Singapore, NUS Ctr Canc Res, Yong Loo Lin Sch Med, Singapore 117599, Singapore.;Fullwood, MJ (通讯作者)，ASTAR, Inst Mol & Cell Biol, Singapore 138673, Singapore.

GENOME RESEARCH, 2022; 32 (4): 629

Abstract

The MYC oncogene encodes for the MYC protein and is frequently dysregulated across multiple cancer cell types, making it an attractive target for canc......

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