Antifibrotic Drug Nintedanib Inhibits CSF1R to Promote IL-4-associated Tissue Repair Macrophages

Watson, CK; Schloesser, D; Fundel-Clemens, K; Lerner, C; Gabler, S; Baskaran, P; Wohnhaas, CT; Dichtl, S; Huber, HJ; Ask, K; Gantner, F; Viollet, C; Thomas, MJ; Ramirez, F; Murray, PJ; El Kasmi, KC

El Kasmi, KC (通讯作者),Boehringer Ingelheim Pharma GmbH & Co KG, D-88397 Biberach, Germany.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2023; 68 (4): 366

Abstract

Profibrotic and prohomeostatic macrophage phenotypes remain ill-defined, both in vivo and in vitro, impeding the successful development of drugs that ......

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