BET inhibition targets ABC-DLBCL constitutive B-cell receptor signaling through PAX5

Oien, DB; Sharma, S; Hattersley, MM; DuPont, M; Criscione, SW; Prickett, L; Goeppert, AU; Drew, L; Yao, Y; Zhang, JW; Chan, HM

Oien, DB; Chan, HM (通讯作者)，AstraZeneca, Early Oncol, 35 Gatehouse Dr, Waltham, MA 02451 USA.

BLOOD ADVANCES, 2023; 7 (17): 5108

Abstract

B-cell receptor (BCR) signaling is essential for the diffuse large B-cell lymphoma (DLBCL) subtype that originates from activated B-cells (ABCs). ABC-......

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