Differences in Cancer Phenotypes Among Frequent CHEK2 Variants and Implications for Clinical Care-Checking CHEK2

Bychkovsky, BL; Agaoglu, NB; Horton, C; Zhou, J; Yussuf, A; Hemyari, P; Richardson, ME; Young, C; LaDuca, H; McGuinness, DL; Scheib, R; Garber, JE; Rana, HQ

Bychkovsky, BL (通讯作者)，Dana Farber Canc Inst, 450 Brookline Ave, Boston, MA 02215 USA.

JAMA ONCOLOGY, 2022; 8 (11): 1598

Abstract

IMPORTANCE Germline CHEK2 pathogenic variants (PVs) are frequently detected by multigene cancer panel testing (MGPT), but our understanding of PVs bey......

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