PEGylation of anti-MerTK Antibody Modulates Ocular Biodistribution

Vollmar, BS; Fei, MJ; Liang, WC; Bravo, DD; Wang, JY; Yu, LL; Corr, N; Zhang, G; McNamara, E; Masih, S; Chee, E; Shin, G; Ohri, R; Leipold, DD; Wu, C; Dere, E; Wang, JY; Huang, HC; Wu, Y; Yan, MH

Vollmar, BS (通讯作者),Genentech Inc, San Francisco, CA 94080 USA.

BIOCONJUGATE CHEMISTRY, 2022; 33 (10): 1837

Abstract

Here, we explore whether PEGylation of antibodies can modulate their biodistribution to the eye, an organ once thought to be immune privileged but has......

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