Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9)

Mussari, CP; Dodd, DS; Sreekantha, RK; Pasunoori, L; Wan, HH; Posy, SL; Critton, D; Ruepp, S; Subramanian, M; Watson, A; Davies, P; Schieven, GL; Salter-Cid, LM; Srivastava, R; Tagore, DM; Dudhgaonkar, S; Poss, MA; Carter, PH; Dyckman, AJ

Dyckman, AJ (corresponding author), Bristol Myers Squibb Res & Dev, Princeton, NJ 08543 USA.

ACS MEDICINAL CHEMISTRY LETTERS, 2020; 11 (9): 1751

Abstract

The toll-like receptor (TLR) family is an evolutionarily conserved component of the innate immune system, responsible for the early detection of forei......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索