Application of physiologically based pharmacokinetic modeling to predict the pharmacokinetics of telavancin in obesity with renal impairment

Wu, WH; Ke, M; Ye, LL; Lin, CH

Lin, CH (corresponding author), Fujian Med Univ, Dept Pharm, Affiliated Hosp 1, 20 Cha Zhong M Rd, Fuzhou 350005, Peoples R China.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, ; ():

Abstract

Purpose U.S. Food and Drug Administration (FDA) recommended telavancin dosing is based on total body weight (TBW) but lacks adjusted regimens for obes......

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