The clinical efficacy of combinatorial therapy of EGFR-TKI and crizotinib in overcoming MET amplification-mediated resistance from prior EGFR-TKI therapy

Wang, YB; Tian, PW; Xia, L; Li, L; Han, R; Zhu, MX; Lizaso, A; Qin, T; Li, M; Yu, B; Mao, XR; Han, HZ; He, Y

He, Y (corresponding author), Army Med Univ, Daping Hosp, Dept Resp Med, 10 Changjiang Branch Rd, Chongqing 400042, Peoples R China.

LUNG CANCER, 2020; 146 (): 165

Abstract

Background: : MET amplification is one of the EGFR-independent mechanisms of EGFR tyrosine kinase inhibitor (TKI) resistance. Combinatorial therapy of......

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