Quinolone antibiotic derivatives as new selective Axl kinase inhibitors

Tan, L; Zhang, Z; Gao, DL; Chan, SP; Luo, JF; Tu, ZC; Zhang, ZM; Ding, K; Ren, XM; Lu, XY

Ding, K; Ren, XM; Lu, XY (reprint author), Jinan Univ, Int Cooperat Lab Tradit Chinese Med Modernizat &, Minist Educ MOE Peoples Republ China, 601 Huangpu Ave West, Guangzhou 510632, Guangdong, Peoples R China.; Ding, K; Ren, XM; Lu, XY (reprint author),

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019; 166 (): 318

Abstract

Axl is a new promising molecular target for antineoplastic therapies. A series of quinolone antibiotic derivatives were designed and synthesized as ne......

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