Increasing Tau 4R Tau Levels Exacerbates Hippocampal Tau Hyperphosphorylation in the hTau Model of Tauopathy but Also Tau Dephosphorylation Following Acute Systemic Inflammation

Barron, MR; Gartlon, J; Dawson, LA; Atkinson, PJ; Pardon, MC

Pardon, MC (corresponding author), Univ Nottingham, Queens Med Ctr, Med Sch, Sch Life Sci,Div Physiol Pharmacol & Neurosci, Nottingham, England.

FRONTIERS IN IMMUNOLOGY, 2020; 11 ():

Abstract

Inflammation is considered a mechanistic driver of Alzheimer's disease, thought to increase tau phosphorylation, the first step to the formation of ne......

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