Impaired dynamic X-chromosome inactivation maintenance in T cells is a feature of spontaneous murine SLE that is exacerbated in female-biased models

Jiwrajka, N; Toothacre, NE; Beethem, ZT; Sting, S; Forsyth, KS; Dubin, AH; Driscoll, A; Stohl, W; Anguera, MC

Anguera, MC (通讯作者),Univ Penn, Dept Biomed Sci, Sch Vet Med, Philadelphia, PA 19104 USA.

JOURNAL OF AUTOIMMUNITY, 2023; 139 ():

Abstract

Objective: Systemic lupus erythematosus (SLE) is a highly female-biased systemic autoimmune disease, but the molecular basis for this female bias rema......

Full Text Link