KRAS mutation as a predictor of insufficient trastuzumab efficacy and poor prognosis in HER2-positive advanced gastric cancer

Shimozaki, K; Shinozaki, E; Yamamoto, N; Imamura, Y; Osumi, H; Nakayama, I; Wakatsuki, T; Ooki, A; Takahari, D; Ogura, M; Chin, K; Watanabe, M; Yamaguchi, K

Shinozaki, E (通讯作者)，Japanese Fdn Canc Res, Dept Gastrointestinal Oncol, Canc Inst Hosp, Koto Ku, Ariake 3-8-3, Tokyo, Japan.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023; 149 (3): 1273

Abstract

Purpose Although RAS and PIK3CA mutations have been associated with resistance to anti-EGFR antibody in colorectal cancer or trastuzumab in breast can......

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