Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity

Pao, KC; Wood, NT; Knebel, A; Rafie, K; Stanley, M; Mabbitt, PD; Sundaramoorthy, R; Hofmann, K; van Aalten, DMF; Virdee, S

Virdee, S (reprint author), Univ Dundee, MRC Prot Phosphorylat & Ubiquitylat Unit, Dundee, Scotland.

NATURE, 2018; 556 (7701): 381

Abstract

Ubiquitination is initiated by transfer of ubiquitin (Ub) from a ubiquitin-activating enzyme (E1) to a ubiquitin-conjugating enzyme (E2), producing a ......

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