Combined, elobixibat, and colestyramine reduced cholesterol toxicity in a mouse model of metabolic dysfunction-associated steatotic liver disease

Iwaki, M; Kessoku, T; Tanaka, K; Ozaki, A; Kasai, Y; Kobayashi, T; Nogami, A; Honda, Y; Ogawa, Y; Imajo, K; Usuda, H; Wada, K; Kobayashi, N; Saito, S; Nakajima, A; Yoneda, M

Yoneda, M (通讯作者),Yokohama City Univ, Dept Gastroenterol & Hepatol, Grad Sch Med, 3-9 Fukuura,Kanazawa Ku, Yokohama 2360004, Japan.

HEPATOLOGY COMMUNICATIONS, 2023; 7 (11):

Abstract

Background: Cholesterol levels and bile acid metabolism are important drivers of metabolic dysfunction-associated steatohepatitis (MASH) progression. ......

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