Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival

Fukuda, Y; Pazyra-Murphy, MF; Silagi, ES; Tasdemir-Yilmaz, OE; Li, YH; Rose, L; Yeoh, ZC; Vangos, NE; Geffken, EA; Seo, HS; Adelmant, G; Bird, GH; Walensky, LD; Marto, JA; Dhe-Paganon, S; Segal, RA

Segal, RA (corresponding author), Harvard Med Sch, Dept Neurobiol, Boston, MA 02115 USA.; Segal, RA (corresponding author), Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02115 USA.

JOURNAL OF CELL BIOLOGY, 2021; 220 (1):

Abstract

Complex neural circuitry requires stable connections formed by lengthy axons. To maintain these functional circuits, fast transport delivers RNAs to d......

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