Allopurinol Protects Against Cholestatic Liver Injury in Mice Not Through Depletion of Uric Acid

Liu, J; Fan, Y; Yu, H; Xu, T; Zhang, CZ; Zhou, LJ; Li, GT; Zhang, YC

Zhang, YC (corresponding author), 92 Weijin Rd, Tianjin 300072, Peoples R China.; Li, GT (corresponding author), 7166 Bao Tong West St, Weifang, Shandong, Peoples R China.

TOXICOLOGICAL SCIENCES, 2021; 181 (2): 295

Abstract

Cholestasis is one of the most severe manifestations of liver injury and has limited therapeutic options. Allopurinol (AP), an inhibitor of uric acid ......

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