Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling

Wei, FH; Jiang, ZM; Sun, HL; Pu, J; Sun, YP; Wang, MY; Tong, Q; Bi, YH; Ma, XJ; Gao, GF; Liu, JH

Wei, FH; Liu, JH (reprint author), China Agr Univ, Coll Vet Med, Minist Agr, Key Lab Anim Epidemiol & Zoonosis, Beijing, Peoples R China.; Wei, FH; Liu, JH (reprint author), China Agr Univ, State Key Lab Agrobiotechnol, Beijing, Peoples R China.; Wei, FH

PLOS PATHOGENS, 2019; 15 (10):

Abstract

Type I interferons (IFNs) play a critical role in host defense against influenza virus infection, and the mechanism of influenza virus to evade type I......

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