beta-Hydroxybutyrate, a Ketone Body, Potentiates the Antioxidant Defense via Thioredoxin 1 Upregulation in Cardiomyocytes

Oka, S; Tang, F; Chin, A; Ralda, G; Xu, XY; Hu, CC; Yang, Z; Abdellatif, M; Sadoshima, J

Sadoshima, J (corresponding author), Rutgers New Jersey Med Sch, Dept Cell Biol & Mol Med, Newark, NJ 07103 USA.

ANTIOXIDANTS, 2021; 10 (7):

Abstract

Thioredoxin 1 (Trx1) is a major antioxidant that acts adaptively to protect the heart during the development of diabetic cardiomyopathy. The molecular......

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