Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-alpha Activation

Zhang, J; Cheng, P; Dai, WQ; Ji, J; Wu, LW; Feng, J; Wu, JY; Yu, Q; Li, JJ; Guo, CY

Li, JJ (corresponding author), Tongji Univ, Sch Med, Dept Gastroenterol, Shanghai Tenth Peoples Hosp, Shanghai 200072, Peoples R China.; Li, JJ (corresponding author), Tongji Univ, Putuo Peoples Hosp, Dept Gastroenterol, Sch Med, Shanghai 200060, Peoples R China.

PPAR RESEARCH, 2021; 2021 ():

Abstract

Hepatic ischemia and reperfusion injury is characterized by hepatocyte apoptosis, impaired autophagy, and oxidative stress. Fenofibrate, a commonly us......

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