Rationale and design of the Medical Research Council's Precision Medicine with Zibotentan in Microvascular Angina (PRIZE) trial

Morrow, AJ; Ford, TJ; Mangion, K; Kotecha, T; Rakhit, R; Galasko, G; Hoole, S; Davenport, A; Kharbanda, R; Ferreira, VM; Shanmuganathan, M; Chiribiri, A; Perera, D; Rahman, H; Arnold, JR; Greenwood, JP; Fisher, M; Husmeier, D; Hill, NA; Luo, XY; Williams, N; Miller, L; Dempster, J; Macfarlane, PW; Welsh, P; Sattar, N; Whittaker, A; Mc Connachie, A; Padmanabhan, S; Berry, C

Berry, C (corresponding author), Univ Glasgow, British Heart Fdn Glasgow Cardiovasc Res Ctr, Inst Cardiovasc & Med Sci, 126 Univ Pl, Glasgow G12 8TA, Lanark, Scotland.

AMERICAN HEART JOURNAL, 2020; 229 (): 70

Abstract

Background Microvascular angina is caused by cardiac small vessel disease, and dysregulation of the endothelin system is implicated. The minor G allel......

Full Text Link