Insulin injections inhibits PTZ-induced mitochondrial dysfunction, oxidative stress and neurological deficits via the SIRT1/PGC-1 alpha/SIRT3 pathway

Cheng, YH; Zeng, X; Mai, QT; Bai, XY; Jiang, Y; Li, JJ; Fan, SQ; Ding, H

Ding, H (corresponding author), Wuhan Univ, Wuhan Univ Sch Pharmaceut Sci, Key Lab Combinatorial Biosynth & Drug Discovery, Minist Educ, Wuhan, Hubei, Peoples R China.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2021; 1867 (6):

Abstract

With an associated 20% death risk, epilepsy mainly involves seizures of an unpredictable and recurrent nature. This study was designed to evaluate the......

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