Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice

Gou, SH; Li, BB; Ouyang, X; Ba, ZF; Zhong, C; Zhang, TY; Chang, LL; Zhu, YW; Zhang, JY; Zhu, NY; Zhang, Y; Liu, H; Ni, JM

Ni, JM (corresponding author), Lanzhou Univ, Sch Pharm, Inst Pharmaceut, Lanzhou 730000, Peoples R China.; Ni, JM (corresponding author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.

JOURNAL OF MEDICINAL CHEMISTRY, 2021; 64 (15): 11247

Abstract

The emergence of multidrug-resistant bacteria has major issues for treating bacterial pneumonia. Currently, anoplin (GLLKRIKTLL-NH2) is a natural anti......

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