DNA (cytosine-5)-methyltransferase 3B (DNMT 3B) polymorphism and risk of Down syndrome offspring

de Moura, CM; Bastos, PR; Ribeiro, JSV; Ribeiro, MG; Amorim, MR; Costa-Lima, MA

Costa-Lima, MA (reprint author), Univ Estado Rio de Janeiro, Inst Biol Roberto Alcantara Gomes, Dept Genet, Lab Genet Mol Humana,PHLC, Rua Sao Francisco Xavier 524,Sala 218, BR-20550900 Rio De Janeiro, Brazil.

SAUDI JOURNAL OF BIOLOGICAL SCIENCES, 2018; 25 (1): 101

Abstract

Down syndrome (DS) is the most common form of human genetic mental retardation. Several polymorphisms in genes coding folic acid cycle enzymes have be......

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