Activation of Human CD11b(+) B1 B-Cells by Trypanosoma cruzi-Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease

Passos, LSA; Magalhaes, LMD; Soares, RP; Marques, AF; Alves, MLR; Giunchetti, RC; Nunes, MDP; Gollob, KJ; Dutra, WO

Dutra, WO (reprint author), Inst Ciencias Biol, Lab Cell Cell Interact, Dept Morfol, Belo Horizonte, MG, Brazil.; Dutra, WO (reprint author), Univ Fed Minas Gerais, Posgrad Parasitol, Belo Horizonte, MG, Brazil.; Dutra, WO (reprint author), Inst Nacl Cien

FRONTIERS IN IMMUNOLOGY, 2019; 9 ():

Abstract

B-cells mediate humoral adaptive immune response via the production of antibodies and cytokines, and by inducing T-cell activation. These functions ca......

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