20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-alpha/caspase8 signaling cascades-MedSci.cn

20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-alpha/caspase8 signaling cascades

Zhu, SR; Liu, XL; Xue, M; Li, Y; Cai, DH; Wang, SJ; Zhang, L

Zhang, L (corresponding author), Nanjing Univ Chinese Med, Sch Pharm, Jiangsu Key Lab Pharmacol & Safety Evaluat Chines, Nanjing 210023, Jiangsu, Peoples R China.

JOURNAL OF GINSENG RESEARCH, 2021; 45 (2): 295

Abstract

Background: Acute promyelocytic leukemia (APL) is a hematopoietic malignancy driven by promyelocytic leukemia-retinoic acid receptor A (PML-RARA) fusi......

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