Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma

Cheng, Y; Gunasegaran, B; Singh, HD; Dutertre, CA; Loh, CY; Lim, JQ; Crawford, JC; Lee, HK; Zhang, XM; Lee, B; Becht, E; Lim, WJ; Yeong, J; Chan, CY; Chung, A; Goh, BKP; Chow, PKH; Chan, JKY; Ginhoux, F; Tai, D; Chen, JM; Lim, SG; Zhai, W; Choo, SP; Newell, EW

Newell, EW (corresponding author), ASTAR, Singapore Immunol Network, 8A Biomed Grove, Singapore 138648, Singapore.; Newell, EW (corresponding author), Fred Hutchinson Canc Res Ctr, Vaccine & Infect Dis Div, 1100 Fairview Ave N, Seattle, WA 98109 USA.

IMMUNITY, 2021; 54 (8): 1825

Abstract

Hepatocellular carcinoma (HCC) often develops following chronic hepatitis B virus (HBV) infection and responds poorly to immune checkpoint blockade. H......

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