Pyoderma gangrenosum: proposed pathogenesis and current use of biologics with an emphasis on complement C5a inhibitor IFX-1

Lu, JD; Milakovic, M; Ortega-Loayza, AG; Marzano, AV; Alavi, A

Alavi, A (corresponding author), Mayo Clin, Dept Dermatol, Rochester, MN 55905 USA.

EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2020; 29 (11): 1179

Abstract

Introduction Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis with no FDA-approved treatment. The complement pathway has received renewed a......

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