ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response

Wang, C; Zhang, MZ; Garcia, G; Tian, E; Cui, Q; Chen, XW; Sun, GH; Wang, JH; Arumugaswami, V; Shi, YH

Shi, YH (corresponding author), Beckman Res Inst City Hope, Dept Dev & Stem Cell Biol, Div Stem Cell Biol Res, Duarte, CA 91010 USA.; Arumugaswami, V (corresponding author), Univ Calif Los Angeles, Dept Mol & Med Pharmacol, Los Angeles, CA 90095 USA.; Arumugaswami, V (corresponding author), Univ Calif Los Angeles, Eli & Edythe Broad Ctr Regenerat Med & Stem Cell, Los Angeles, CA 90095 USA.

CELL STEM CELL, 2021; 28 (2): 331

Abstract

ApoE4, a strong genetic risk factor for Alzheimer disease, has been associated with increased risk for severe COVID-19. However, it is unclear whether......

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