Asymmetric Synthesis of (-)-Colchicine and Its Natural Analog (-)-N-Acetylcolchicine Methyl Ether

Pu, LY; Li, ZY; Li, LM; Ma, YC; Ma, M; Hu, SQ; Wu, ZZ

Ma, M (通讯作者)，Jinan Univ, Integrated Chinese & Western Med Postdoctoral Res, Guangzhou 510632, Peoples R China.;Hu, SQ; Wu, ZZ (通讯作者)，Shenzhen Univ, Shenzhen Peoples Hosp 2, Shenzhen Inst Translat Med, Affiliated Hosp 1, Shenzhen 518035, Guangdong, Peoples R China.;Hu, SQ; Wu, ZZ (通讯作者)，Shenzhen Inst Geriatr, Shenzhen 518035, Guangdong, Peoples R China.

CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023; 43 (1): 313

Abstract

(-)-Colchicine and its natural analogue (-)-N-acetylcolchinol methyl ether have been synthesized in a com-paratively conciser asymmetric synthetic app......

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