Durable Control of Metastatic AKT1-Mutant WHO Grade 1 Meningothelial Meningioma by the AKT Inhibitor, AZD5363

Weller, M; Roth, P; Sahm, F; Burghardt, I; Schuknecht, B; Rushing, EJ; Regli, L; Lindemann, JP; von Deimling, A

Weller, M (reprint author), Univ Zurich Hosp, Dept Neurol, Frauenklin Str 26, CH-8091 Zurich, Switzerland.; Weller, M (reprint author), Univ Zurich Hosp, Brain Tumor Ctr, Frauenklin Str 26, CH-8091 Zurich, Switzerland.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2017; 109 (3):

Abstract

High-throughput analyses have revealed the presence of activating mutations in the AKT1 gene in a subpopulation of meningiomas. We report a female pat......

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