Digoxin, an Overlooked Agonist of ROR gamma/ROR gamma T

Karas, K; Salkowska, A; Sobalska-Kwapis, M; Walczak-Drzewiecka, A; Strapagiel, D; Dastych, J; Bachorz, RA; Ratajewski, M

Ratajewski, M (reprint author), Polish Acad Sci, Inst Med Biol, Lab Epigenet, Lodz, Poland.

FRONTIERS IN PHARMACOLOGY, 2019; 9 ():

Abstract

Digoxin was one of the first identified ROR gamma T receptor inverse agonists inhibiting the differentiation of Th17 cells. However, this compound exh......

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