Physiologically Based Pharmacokinetic Models Are Effective Support for Pediatric Drug Development

Wang, KF; Jiang, K; Wei, XY; Li, YL; Wang, TJ; Song, Y

Song, Y (corresponding author), China Med Univ, Sch Pharm, Shenyang 110122, Peoples R China.; Wang, TJ (corresponding author), Shenzhen Inst Drug Control, NMPA Key Lab Bioequivalence Res Gener Drug Evalua, Shenzhen 518057, Peoples R China.

AAPS PHARMSCITECH, 2021; 22 (6):

Abstract

Pediatric drug development faces many difficulties. Traditionally, pediatric drug doses are simply calculated linearly based on the body weight, age, ......

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