PET imaging of mGluR5 in Alzheimer's disease

Mecca, AP; McDonald, JW; Michalak, HR; Godek, TA; Harris, JE; Pugh, EA; Kemp, EC; Chen, MK; Salardini, A; Nabulsi, NB; Lim, K; Huang, YY; Carson, RE; Strittmatter, SM; van Dyck, CH

ALZHEIMERS RESEARCH & THERAPY, 2020; 12 (1):

Abstract

Background Metabotropic glutamate subtype 5 receptors (mGluR5) modulate synaptic transmission and may constitute an important therapeutic target in Al......

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