DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A

Huang, YH; Su, JZ; Lei, Y; Brunetti, L; Gundry, MC; Zhang, XT; Jeong, M; Li, W; Goodell, MA

Goodell, MA (reprint author), Baylor Coll Med, Dept Dev Biol, Houston, TX 77030 USA.; Goodell, MA (reprint author), Baylor Coll Med, Stem Cells & Regenerat Med Ctr, Houston, TX 77030 USA.; Goodell, MA (reprint author), Baylor Coll Med, Ctr Cell & Gene The

GENOME BIOLOGY, 2017; 18 ( ):

Abstract

Background: DNA methylation has widespread effects on gene expression during development. However, our ability to assign specific function to regions ......

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