Disulfiram alleviates acute lung injury and related intestinal mucosal barrier impairment by targeting GSDMD-dependent pyroptosis

Zhao, JP; Wang, H; Zhang, JT; Ou, FW; Wang, JF; Liu, T; Wu, JX

Wu, JX (通讯作者),Shandong Univ, Qilu Hosp, Cheeloo Coll Med, Dept Pulm & Crit Care Med, Jinan, Peoples R China.

JOURNAL OF INFLAMMATION-LONDON, 2022; 19 (1):

Abstract

Background Pyroptosis was implicated in acute lung injury (ALI). Disulfiram is reported as an effective pyroptosis inhibitor by inhibiting gasdermin D......

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