Leucine-rich repeat kinase 2 (LRRK2) inhibitors differentially modulate glutamate release and Serine935 LRRK2 phosphorylation in striatal and cerebrocortical synaptosomes

Mercatelli, D; Bolognesi, P; Frassineti, M; Pisano, CA; Longo, F; Shimshek, DR; Morari, M

Morari, M (reprint author), Univ Ferrara, Dept Med Sci, Sect Pharmacol, Via Fossato Mortara 17-19, I-44122 Ferrara, Italy.

PHARMACOLOGY RESEARCH & PERSPECTIVES, 2019; 7 (3):

Abstract

Mutations in leucine-rich repeat kinase 2 (LRRK2) gene have been pathogenically linked to Parkinson's disease, and pharmacological inhibition of LRRK2......

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