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Serine Integrase attP Binding and Specificity

Treatment of aTTP: start Caplacizumab early

Targeted integration into pseudo attP sites of CHO cells using CRISPR/Cas9

Approach the aTTP with a watchful eye

Caplacizumab for the Treatment of acquired thrombotic thrombocytopenic Purpura (aTTP)

ADAMTS13 and VWF activities guide individualized caplacizumab treatment in patients with aTTP

Parallel Genomic Engineering of Two Drosophila Genes Using Orthogonal attB/attP Sites

aTTP: How a Nanobody prevents the life-threatening Formation of Microthrombi

Thrombocytopenia with Fragmentocytes in the Blood Smear: Initiate Plasmapheresis even if aTTP is suspectedCaplacizumab is the first therapeutic Antibody to specifically treat an aTTP Episode in Adults

IDENTIFY PATIENTS WITH RARE DISEASES IN PORTUGAL: ACQUIRED THROMBOTIC THROMBOCYTOPENIC PURPURA (ATTP)

Robust phi C31-Mediated Genome Engineering in Drosophila melanogaster Using Minimal attP/attB Phage Sites

Rapid characterization of the CHO platform cell line and identification of pseudo attP sites for PhiC31

Using a phiC31 "Disintegrase" to make new attP sites in the Drosophila genome at locations showing chromosomal

Caplacizumab The first approved Therapy Option for aTTP has proven itself in the Practice

CAPLACIZUMAB FOR THE TREATMENT OF ACQUIRED THROMBOTIC THROMBOCYTOPENIC PURPURA (ATTP): TECHNOLOGY QUALIFICATION

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