ESC2016:多支血管病变是一次解决还是多次再通?

2016-08-29 Tylen 心血管时间

%; clear: both; min-height: 1em; box-sizing: border-box !important; word-wrap: break-word !important;">2.3.1 预防和治疗蒽环类药物导致的心脏毒性减少累计用量;儿童使用持续用药方法(至多 48~96 小时)减少达峰浓度;使用类似物替代(比如表阿霉素等);使用脂质体结构的药物;避免使用紫杉烷类等

2016 年 8 月 27 日~31 日,欧洲心脏病学会年会(ESC2016)在意大利罗马盛大召开。


来自韩国忠南大学附属医院的 J.O. Jeong 等将在大会上发表关于多支血管病变(MVCD)治疗策略的研究。


对于 ST 段抬高型心梗(STEMI)合并多支血管病变的患者,目前有多种针对非梗死相关动脉的处理方案:急诊 PCI 时直接在多支血管中植入支架和阶段性地血管再通。该研究旨在对比这两种策略对死亡率的影响。


该研究纳入了 2011 年至 2015 年间,1078 例注册入院的 STEMI 合并 MVCD 患者(平均年龄为 63.2 岁,21.8% 位女性)。


患者被分为 2 组:急诊 PCI 术后再行阶段性 PCI 治疗(600 例);急诊 PCI 时同时对多支血管植入支架处理(478 例)。研究对两组间主要心血管事件和心血管疾病导致的死亡进行分析。


结果表明,相比同时多血管处理组,阶段性 PCI 组在心血管疾病导致的死亡、主要不良心血管事件方面都明显较低。校正临床变量之后,尽管两组间的主要不良心血管事件并没有明显差异,但阶段性 PCI 组的心血管疾病导致的死亡却明显较少。


对于心源性休克的患者,阶段性 PCI 的临床获益更加明显。Cox 回归分析也肯定了阶段性 PCI 对心血管疾病死亡的作用。


总之,对于多支血管病变的 STEMI 患者,相比急诊 PCI 时同时处理多支血管,急诊 PCI 后再行阶段性 PCI 可减少心源性死亡。


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    2016-09-25 1e10c84am36(暂无匿称)

    文章很好值得关注

    0

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    2016-08-30 大旺旺

    学习了啊

    0

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    2016-08-30 doctorJiangchao

    继续学习

    0

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    2016-08-30 doctorJiangchao

    继续关注

    0

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