治疗股骨头坏死可不必换关节,新技术提高中早期保髋率

2017-05-08 许珈 澎湃新闻

股骨头坏死是骨科临床常见的疑难疾病,目前对于该病的治疗方法单一,仍以终末期人工髋关节置换为主,对中早期患者“束手无策”。上海交通大学附属第六人民医院骨科张长青教授团队历时 15 年,建立了一系列中早期股骨头坏死的关键外科技术,使股骨头坏死“治疗窗”提前至早中期,将保髋率由 59%提高至 86%。张长青教授点开手机,翻出来一张合影,照片上的女孩小云(匿名)笑容灿烂。你不会想到,女孩13岁那年曾因事故

股骨头坏死是骨科临床常见的疑难疾病,目前对于该病的治疗方法单一,仍以终末期人工髋关节置换为主,对中早期患者“束手无策”。上海交通大学附属第六人民医院骨科张长青教授团队历时 15 年,建立了一系列中早期股骨头坏死的关键外科技术,使股骨头坏死“治疗窗”提前至早中期,将保髋率由 59%提高至 86%。

张长青教授点开手机,翻出来一张合影,照片上的女孩小云(匿名)笑容灿烂。你不会想到,女孩13岁那年曾因事故差点失去了站立与行走的机会。

股骨头坏死是骨科临床常见的疑难疾病,对患者及其家庭乃至社会影响巨大。患者本身别说行走,就算站立都痛不欲生。大部分情况下,只能卧床,等待人工髋关节置换。像小云这样13岁就出现坏死的情况,治疗就更加困难。虽然,人工髋关节置换可以帮助她,但临床上,这种方法对未成年人并不适合。因为未成年人还在生长发育期,即便换上了人工髋关节,也无法长久,因为本身的骨头还在继续生长,人工的髋关节却是固定的。

可如果不换人工髋关节,小云就得一直卧床,在病痛中等待自己成年。对于一个13岁的孩子而言,这种痛苦旁人难以体会。即便等到了换人工髋关节的那天,那么多年未下地的她,肌肉、骨骼也都退化了。更主要的是,原本属于她学习、玩乐的日子,也都一去不复返了。

对于未成年患者,张长青团队进行了新的研究,尝试打破禁区,展开“重建”手术。小云就是受益者。经过重建,小云可以重新站立、行走,这些年的随访中,也进行了几次“微调”,普通的日常活动都不成问题。

或许大家会认为,小云这种情况都是特例,哪来那么多意外?现实却并非如此。引起股骨头坏死的原因可以分为两大类。一类是创伤性股骨头坏死,小云就属于这种。另一类则是非创伤性股骨头坏死,在这部分人中,中青年是大多数。

张长青教授介绍,非创伤性股骨头坏死常发生于中青年身上,平均发生年龄在38岁左右,只有20%的人超过50岁。

需要提醒的是,虽然非创伤原因引起的股骨头坏死通常与一个或多个因素有关,但约60%的非创伤性股骨头坏死与皮质醇增多症及酒精过度摄入有关。另外,镰状红细胞性骨坏死、减压病、妊娠、放射线性骨坏死、艾滋病等也会引起,但为少数情况。

任何一种疾病从发生到发作都有一个过程。以往,一旦确认患者股骨头坏死,那就只有一个选择,等待置换人工关节。但对于中青年而言,能用自己的关节总好过用人工。而且,人工关节也并非每个人都能换,即便换了,后续也有其他问题考虑。比如,关节功能受限、力量减小等等。更关键的是,年纪轻轻就置换人工关节,日后势必要翻修。每一次翻修,造成的出血和手术创伤都是不可估量的。针对这种情况,张长青教授聚焦中早期保髋治疗,历时 15 年,建立了一系列中早期股骨头坏死的外科技术,使股骨头坏死“治疗窗”提前至早中期,将保髋率由 59%提高至 86%。

此外,张长青教授团队在国际上首次证实青少年股骨头坏死可通过腓骨移植进行重建,80%的青少年股骨头坏死患者经治疗后明显改善了髋关节形态,髋关节功能得以保留。“20岁以下的年轻人,即便是股骨头坏死晚期,经过重建也可以让髋关节延长10-30年寿命,有些患者甚至可以达到终身治疗。”张长青教授说。

对于青少年患者而言,这一次突破,或许真能改变他们的一生。

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    2017-09-06 redcrab
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    2017-06-07 戒馋,懒,贪

    与带血管蒂的骨瓣移植有什么区别?说的不甚详细啊,就是个新闻啊

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1721832, encodeId=26061e218326c, content=<a href='/topic/show?id=01811016363e' target=_blank style='color:#2F92EE;'>#骨头#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101636, encryptionId=01811016363e, topicName=骨头)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9cd033099978, createdName=redcrab, createdTime=Wed Sep 06 08:07:00 CST 2017, time=2017-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=207619, encodeId=4bcc20e61974, content=与带血管蒂的骨瓣移植有什么区别?说的不甚详细啊,就是个新闻啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Wed Jun 07 08:36:38 CST 2017, time=2017-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1903758, encodeId=4e961903e5887, content=<a href='/topic/show?id=be285836438' target=_blank style='color:#2F92EE;'>#新技术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58364, encryptionId=be285836438, topicName=新技术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d39f177, createdName=lixiao3326, createdTime=Mon Sep 04 06:07:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197743, encodeId=285419e743af, content=不同年龄阶段的股骨头坏死,选用不同的治疗方案, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=39ef2044909, createdName=zmj4567, createdTime=Sun May 14 01:02:34 CST 2017, time=2017-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1362827, encodeId=b0f6136282e72, content=<a href='/topic/show?id=b723414321c' target=_blank style='color:#2F92EE;'>#坏死#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41432, encryptionId=b723414321c, topicName=坏死)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0e3195, createdName=millore, createdTime=Wed May 10 12:07:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529679, encodeId=323d15296e96d, content=<a href='/topic/show?id=70ff81e9156' target=_blank style='color:#2F92EE;'>#股骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81791, encryptionId=70ff81e9156, topicName=股骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9d3011964327, createdName=wangyang7962, createdTime=Wed May 10 12:07:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1584875, encodeId=1dad15848e58e, content=<a href='/topic/show?id=931581e97ad' target=_blank style='color:#2F92EE;'>#股骨头#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81797, encryptionId=931581e97ad, topicName=股骨头)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ee217064831, createdName=huagfeg, createdTime=Wed May 10 12:07:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195768, encodeId=c59f195e68de, content=学习。。。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLEjPHcBWkEawnOHuvuXw3Lxjnzko8jRkakGyVZ27zRcmYACibkCom9Da1icAJBDFrbJelRNtMRic3H3/0, createdBy=152c1940043, createdName=Lke, createdTime=Tue May 09 09:02:54 CST 2017, time=2017-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195628, encodeId=1e681956287d, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Tue May 09 06:39:56 CST 2017, time=2017-05-09, status=1, ipAttribution=)]
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    2017-05-14 zmj4567

    不同年龄阶段的股骨头坏死,选用不同的治疗方案

    0

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    2017-05-10 millore
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    2017-05-10 huagfeg
  8. [GetPortalCommentsPageByObjectIdResponse(id=1721832, encodeId=26061e218326c, content=<a href='/topic/show?id=01811016363e' target=_blank style='color:#2F92EE;'>#骨头#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101636, encryptionId=01811016363e, topicName=骨头)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9cd033099978, createdName=redcrab, createdTime=Wed Sep 06 08:07:00 CST 2017, time=2017-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=207619, encodeId=4bcc20e61974, content=与带血管蒂的骨瓣移植有什么区别?说的不甚详细啊,就是个新闻啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Wed Jun 07 08:36:38 CST 2017, time=2017-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1903758, encodeId=4e961903e5887, content=<a href='/topic/show?id=be285836438' target=_blank style='color:#2F92EE;'>#新技术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58364, encryptionId=be285836438, topicName=新技术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d39f177, createdName=lixiao3326, createdTime=Mon Sep 04 06:07:00 CST 2017, time=2017-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197743, encodeId=285419e743af, content=不同年龄阶段的股骨头坏死,选用不同的治疗方案, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=39ef2044909, createdName=zmj4567, createdTime=Sun May 14 01:02:34 CST 2017, time=2017-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1362827, encodeId=b0f6136282e72, content=<a href='/topic/show?id=b723414321c' target=_blank style='color:#2F92EE;'>#坏死#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=41432, encryptionId=b723414321c, topicName=坏死)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0e3195, createdName=millore, createdTime=Wed May 10 12:07:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529679, encodeId=323d15296e96d, content=<a href='/topic/show?id=70ff81e9156' target=_blank style='color:#2F92EE;'>#股骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81791, encryptionId=70ff81e9156, topicName=股骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9d3011964327, createdName=wangyang7962, createdTime=Wed May 10 12:07:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1584875, encodeId=1dad15848e58e, content=<a href='/topic/show?id=931581e97ad' target=_blank style='color:#2F92EE;'>#股骨头#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81797, encryptionId=931581e97ad, topicName=股骨头)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ee217064831, createdName=huagfeg, createdTime=Wed May 10 12:07:00 CST 2017, time=2017-05-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195768, encodeId=c59f195e68de, content=学习。。。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLEjPHcBWkEawnOHuvuXw3Lxjnzko8jRkakGyVZ27zRcmYACibkCom9Da1icAJBDFrbJelRNtMRic3H3/0, createdBy=152c1940043, createdName=Lke, createdTime=Tue May 09 09:02:54 CST 2017, time=2017-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195628, encodeId=1e681956287d, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Tue May 09 06:39:56 CST 2017, time=2017-05-09, status=1, ipAttribution=)]
    2017-05-09 Lke

    学习。。。。。。。。

    0

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    2017-05-09 laoli

    学习了,谢谢分享!

    0

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