Gastroenterology:成年结肠癌患者生存率种族差异的影响因素研究

2017-11-14 zhangfan MedSci原创

研究认为,对于18-64岁结肠癌患者保险和肿瘤特征差异是导致患者生存期种族差异的最重要因素,完善的医疗保险制度将有助于降低黑人人群结肠癌死亡率

统计发现,美国黑人结肠癌患者的死亡率高于白人患者。先前的研究表明,不同种族老年结肠癌患者的生存期差异影响因素中,肿瘤特征(肿瘤分期、分级、淋巴结状况及合并症)的影响效果要大于治疗差异。近日研究人员在18-64岁结肠癌患者中,考察了造成不同种族患者结肠癌生存期差异的多种影响因素。

研究人员从国家癌症数据库和美国外科学院和美国癌症协会癌症登记数据库中收集相关资料,18-64岁的、在2004-2012年间单独或第一原发性侵入I-IV结肠癌患者参与,从人口统计学、保险、合并症、肿瘤特征和治疗5等方面考察不同种族患者结肠癌生存期差异。

研究发现,黑人和白人患者5年的结肠癌生存率差异为9.2%(黑人患者生存率为57.3% vs 白人患者生存率为66.5%)。人口统计学特征进行匹配后,生存率差异未见显著变化;对保险特征进行匹配后,生存率的绝对差异下降至4.9%,降低了53%;对肿瘤特征进行匹配后,生存率的绝对差异下降至2.3%,差异性降低了74%,其他的影响因素对结肠癌生存率的种族差异影响不显著。在比例风险模型中,保险以及肿瘤特征差异对黑人患者生存率降低的影响分别占54%和27%。

研究认为,对于18-64岁结肠癌患者保险和肿瘤特征差异是导致患者生存期种族差异的最重要因素,完善的医疗保险制度将有助于降低黑人人群结肠癌死亡率。

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    2018-07-07 许安
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  5. 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href='/topic/show?id=144f5032688' target=_blank style='color:#2F92EE;'>#影响因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50326, encryptionId=144f5032688, topicName=影响因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80a06745918, createdName=chenzhuanggui, createdTime=Thu Nov 16 06:38:00 CST 2017, time=2017-11-16, status=1, ipAttribution=)]
    2017-12-25 情途末路

    学习了.获益匪浅!感谢分享

    0

  6. 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    2017-12-03 jyzxjiangqin

    成年结肠癌患者生存率种族差异.

    0

  7. 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    2017-11-25 jyzxjiangqin

    成年结肠癌患者生存率研究.

    0

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